Reverse transcriptase-free detection of viral RNA using Hemo Klentaq DNA polymeraseArticle Published on 2022-12-152022-11-15 Journal: Analytical biochemistry [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] affected amplification Analysis can be used caused comparable COVID-19 Degraded RNA demonstrated determine DNA polymerase Efficiency freeze-thaw cycles limitations Nasopharyngeal swab Nearby Nearby primers overcome pandemic patients PCR polymerase chain polymerase chain reaction Primers provide provided reliability reverse transcriptase Reverse transcriptase activity reverse transcription RNA RT-PCR SARS-CoV-2 SARS-CoV-2 detection target transcriptase Viral RNA Viral RNA. [DOI] 10.1016/j.ab.2022.114960 PMC 바로가기
A novel statistical method predicts mutability of the genomic segments of the SARS-CoV-2 virusResearch Article Published on 2022-12-132022-10-29 Journal: Qrb Discovery [Category] COVID-19, [키워드] affected antiviral drugs approach candidate coding regions codon conserved correlated correlation determine develop disease distribution effective epitope Frequency genomic identify immunogenic peptide large-scale analysis mutability offer overcome pandemic pathogenesis of SARS-CoV-2 predict predicted Protein SARS-CoV-2 SARS-CoV-2 virus SARS-CoV2 scientist sequence Seven spike glycoprotein statistical statistical analysis target the SARS-CoV-2 virus treatments for COVID-19 Vaccine viral genome viral mutation whole genome whole genome sequence Word Ranking [DOI] 10.1017/qrd.2021.13 PMC 바로가기 [Article Type] Research Article
The spike receptor-binding motif G496S substitution determines the replication fitness of SARS-CoV-2 Omicron sublineageArticle Published on 2022-12-012022-11-15 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] approach Cell culture circulating comparable contribute COVID-19 determine experimental animal models fitness. G496S genetics monoclonal antibodies omicron Omicron BA.1 Omicron BA.2 pathogenicity phenotype predominant receptor-binding motif Replication SARS-CoV-2 SARS-CoV-2 variant sensitivity spike mutation therapeutic trajectory [DOI] 10.1080/22221751.2022.2111977 PMC 바로가기
Prevalence and Correlates of SARS CoV-2 Among a Community-Based Sample Recruited Using Randomized Venue-Based Sampling. Essex County, NJ, 2020Article Published on 2022-12-012022-11-15 Journal: Journal of racial and ethnic health disparities [Category] COVID19(2023년), SARS, 진단, [키워드] antibody black blood sample Care Community conducted correlates COVID-19 death determine Diagnosis disease Disparities disparity Factor help identify Infection Latinx morbidity and mortality New no significant difference outcome participant Participants PCR testing positive Prevalence provided public health reflected Sample sampling SARS CoV-2 SARS-CoV-2 antibodies Seroprevalence seroprevalence. stick suggested Surveillance Testing the disease Treatment underlying conditions upstream USA virus [DOI] 10.1007/s40615-021-01175-5 PMC 바로가기
Could red cell distribution width be used for predicting cardiac injury in neonates with COVID-19?Article Published on 2022-12-012022-11-15 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 바이오마커, [키워드] Affect all age group calculated coronavirus disease Coronavirus disease 2019 Coronavirus disease 2019 pandemic COVID-19 cut-off value determine Diagnosis died Diseases distribution Fever group Hospitalization illness immature immunologically Inflammation Inflammatory Injury Laboratory life-threatening management nasopharyngeal swab sample Neonatal Neonate Neonates Newborn Patient PCR PCR-positive polymerase chain populations positive Prognosis prognostic prognostic biomarker Prognostic value Red cell Red cell distribution width SARS-CoV-2 SARS-COV-2 infection screened Sensitivity and specificity severe disease significantly higher syndrome systemic inflammatory the patient troponin level troponin levels troponin. were used [DOI] 10.1002/jmv.28050 PMC 바로가기
Evaluation of the Relationship Between Aquaporin-1, Hepcidin, Zinc, Copper, and İron Levels and Oxidative Stress in the Serum of Critically Ill Patients with COVID-19Article Published on 2022-12-012022-11-16 Journal: Biological trace element research [Category] COVID19(2023년), SARS, 치료기술, [키워드] antioxidant aquaporin both groups chronic disease control group copper correlation COVID-19 COVID-19 disease COVID-19 patient COVID-19 patients determine disease severity elements Endotracheal intubation had no healthy hepcidin Ill in viral indicated individual Infection Inpatient intensive care Invasive mechanical ventilation Level negative PCR test oxidative stress parameter patients with COVID-19 relationship Result SARS-CoV-2 separated sera Significant statistically significant TAC the healthy the patient Total Total antioxidant status Total oxidant status trace Trace element Trace elements. two groups with COVID-19 Zinc [DOI] 10.1007/s12011-022-03400-6 PMC 바로가기
Perception and determinants of Social Networking Sites (SNS) on spreading awareness and panic during the COVID-19 pandemic in BangladeshResearch article Published on 2022-12-012022-10-05 Journal: Health Policy OPEN [Category] 치료기술, [키워드] assist Awareness Bangladesh Chi-square collected COVID-19 COVID-19 pandemic determinant determine Facebook form Google highest information Logistic regression Logistic regression analysis media medium misinformation multivariate networking pandemic Panic participant Pearson Perception performed Prevent regulate Research Result reveal significantly Site social media Social networking site Spread survival unique variable variables [DOI] 10.1016/j.hpopen.2022.100075 [Article Type] Research article
A case-case study on the effect of primary and booster immunization with China-produced COVID-19 vaccines on prevention of pneumonia and viral load among vaccinated persons infected by Delta and Omicron variantsDelta 및 Omicron 변종에 감염된 백신 접종자의 폐렴 및 바이러스 부하 예방에 대한 중국산 COVID-19 백신의 1차 및 추가 접종 효과에 대한 사례 연구Article Published on 2022-12-012022-09-11 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 변종, [키워드] administration age analysed association booster booster dose booster immunization calculate case study case-case study COVID-19 COVID-19 outbreak COVID-19 pneumonia COVID-19 vaccine Ct value Ct values Delta determine eligible evaluated immunization Infection infections less Logistic regression no difference no differences Odds ratio Odds ratios omicron pace Pneumonia real-world study. recipient reduced reduction SARS-CoV-2 viral load vaccination Vaccination Status variant Viral load [DOI] 10.1080/22221751.2022.2103455 PMC 바로가기 [Article Type] Article
What are the long-term holistic health consequences of COVID-19 among survivors? An umbrella systematic reviewArticle Published on 2022-12-012022-11-16 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 변종, [키워드] acute COVID-19 acute phase acute respiratory syndrome affected conducted consequence coronavirus COVID-19 COVID-19 treatments demographic data determine eligibility criteria employment Epidemiology fatigue functional Health Impact individual Laboratory parameters memory Pandemics Participants physical Psychological psychological impacts Quality of life ranged Research respiratory symptoms Sample SARS Coronavirus screened survived Survivors systematic review systematic reviews variant virus virus classification. [DOI] 10.1002/jmv.28086 PMC 바로가기
SARS-CoV-2 vaccine booster in solid organ transplant recipients previously immunised with inactivated versus mRNA vaccines: A prospective cohort studyArticle Published on 2022-12-012022-10-06 Journal: Lancet Reg Health Am [Category] 진단, [키워드] age All participant anti-SARS-CoV-2 BNT162b2 BNT162b2 vaccine booster Care cohort study CoronaVac COVID-19 determine dose effective end point General population groups Heterologous heterologous vaccine homologous humoral immune response IFN-γ IgG antibody IL-2 inactivated kidney liver median Medicine more difficult mRNA mRNA vaccine neutralising antibody not differ of BNT162b2 outcome Patient priming proportion Prospective prospective cohort study recipient recipients Red SARS-CoV-2 SARS-CoV-2 vaccine School secondary secreting significantly significantly higher solid organ solid organ transplant SOT T-cell T-cell responses vaccination Vaccine vaccine immunogenicity. women [DOI] 10.1016/j.lana.2022.100371 PMC 바로가기 [Article Type] Article